Cargando…
The Natural Killer T (NKT) Cell Ligand α-Galactosylceramide Demonstrates Its Immunopotentiating Effect by Inducing Interleukin (IL)-12 Production by Dendritic Cells and IL-12 Receptor Expression on NKT Cells
The natural killer T (NKT) cell ligand α-galactosylceramide (α-GalCer) exhibits profound antitumor activities in vivo that resemble interleukin (IL)-12–mediated antitumor activities. Because of these similarities between the activities of α-GalCer and IL-12, we investigated the involvement of IL-12...
Autores principales: | Kitamura, Hidemitsu, Iwakabe, Kenji, Yahata, Takashi, Nishimura, Shin-ichiro, Ohta, Akio, Ohmi, Yasushi, Sato, Marimo, Takeda, Kazuyoshi, Okumura, Ko, Van Kaer, Luc, Kawano, Tetsu, Taniguchi, Masaru, Nishimura, Takashi |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193012/ https://www.ncbi.nlm.nih.gov/pubmed/10190903 |
Ejemplares similares
-
Natural Killer T Cell Ligand α‐Galactosylceramide Inhibited Lymph Node Metastasis of Highly Metastatic Melanoma Cells
por: Nakui, Minoru, et al.
Publicado: (1999) -
Expansion of Lung Vα14 NKT Cells by Administration of α‐Galactosylceramide‐pulsed Dendritic Cells
por: Akutsu, Yasunori, et al.
Publicado: (2002) -
IL-12 and IL-18 Induction and Subsequent NKT Activation Effects of the Japanese Botanical Medicine Juzentaihoto
por: Fujiki, Kazuhiko, et al.
Publicado: (2008) -
Defective NKT Cell Activation by CD1d+ TRAMP Prostate Tumor Cells Is Corrected by Interleukin-12 with alpha-Galactosylceramide
por: Nowak, Michael, et al.
Publicado: (2010) -
Distinct Role of Antigen-Specific T Helper Type 1 (Th1) and Th2 Cells in Tumor Eradication in Vivo
por: Nishimura, Takashi, et al.
Publicado: (1999)