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Microbial Epitopes Act as Altered Peptide Ligands to Prevent Experimental Autoimmune Encephalomyelitis
Molecular mimicry refers to structural homologies between a self-protein and a microbial protein. A major epitope of myelin basic protein (MBP), p87–99 (VHFFKNIVTPRTP), induces experimental autoimmune encephalomyelitis (EAE). VHFFK contains the major residues for binding of this self-molecule to T c...
Autores principales: | Ruiz, Pedro J., Garren, Hideki, Hirschberg, David L., Langer-Gould, Annette M., Levite, Mia, Karpuj, Marcela V., Southwood, Scott, Sette, Alessandro, Conlon, Paul, Steinman, Lawrence |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193020/ https://www.ncbi.nlm.nih.gov/pubmed/10209044 |
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