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Dramatic Rise in Plasma Viremia after CD8(+) T Cell Depletion in Simian Immunodeficiency Virus–infected Macaques

To determine the role of CD8(+) T cells in controlling simian immunodeficiency virus (SIV) replication in vivo, we examined the effect of depleting this cell population using an anti-CD8 monoclonal antibody, OKT8F. There was on average a 99.9% reduction of CD8 cells in peripheral blood in six infect...

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Detalles Bibliográficos
Autores principales:	Jin, Xia, Bauer, Daniel E., Tuttleton, Sarah E., Lewin, Sharon, Gettie, Agegnehu, Blanchard, James, Irwin, Craig E., Safrit, Jeffrey T., Mittler, John, Weinberger, Leor, Kostrikis, Leondios G., Zhang, Linqi, Perelson, Alan S., Ho, David D.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1999
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193038/ https://www.ncbi.nlm.nih.gov/pubmed/10075982

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