Cargando…
Grf40, A Novel Grb2 Family Member, Is Involved in T Cell Signaling through Interaction with SLP-76 and LAT
We molecularly cloned a new Grb2 family member, named Grf40, containing the common SH3-SH2-SH3 motif. Expression of Grf40 is predominant in hematopoietic cells, particularly T cells. Grf40 binds to the SH2 domain–containing leukocyte protein of 76 kD (SLP-76) via its SH3 domain more tightly than Grb...
Autores principales: | Asada, Hiroshi, Ishii, Naoto, Sasaki, Yoshiteru, Endo, Kazuhiro, Kasai, Hirotake, Tanaka, Nobuyuki, Takeshita, Toshikazu, Tsuchiya, Shigeru, Konno, Tasuke, Sugamura, Kazuo |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193052/ https://www.ncbi.nlm.nih.gov/pubmed/10224278 |
Ejemplares similares
-
Involvement of Lat, Gads, and Grb2 in Compartmentation of Slp-76 to the Plasma Membrane
por: Ishiai, Masamichi, et al.
Publicado: (2000) -
Differential Requirement for LAT and SLP-76 in GPVI versus T Cell Receptor Signaling
por: Judd, Barbi A., et al.
Publicado: (2002) -
The adaptor molecules LAT and SLP-76 are specifically targeted by Yersinia to inhibit T cell activation
por: Gerke, Christiane, et al.
Publicado: (2005) -
Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production
Publicado: (1996) -
GrpL, a Grb2-related Adaptor Protein, Interacts with SLP-76 to Regulate Nuclear Factor of Activated T Cell Activation
por: Law, Che-Leung, et al.
Publicado: (1999)