The IKKβ Subunit of IκB Kinase (IKK) is Essential for Nuclear Factor κB Activation and Prevention of Apoptosis

The IκB kinase (IKK) complex is composed of three subunits, IKKα, IKKβ, and IKKγ (NEMO). While IKKα and IKKβ are highly similar catalytic subunits, both capable of IκB phosphorylation in vitro, IKKγ is a regulatory subunit. Previous biochemical and genetic analyses have indicated that despite their...

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Detalles Bibliográficos
Autores principales: Li, Zhi-Wei, Chu, Wenming, Hu, Yinling, Delhase, Mireille, Deerinck, Tom, Ellisman, Mark, Johnson, Randall, Karin, Michael
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193082/
https://www.ncbi.nlm.nih.gov/pubmed/10359587

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