Cargando…

The Interleukin 7 Receptor Is Required for T Cell Receptor γ Locus Accessibility to the V(D)j Recombinase

Defects in the interleukin (IL)-7 signal transduction pathway lead to severe immunodeficiency in humans and in mice. In IL-7 receptor–deficient (IL-7R(−/)−) mice, lymphoid precursors show a reduced survival rate and variable/diversity/joining region V(D)J recombination is variously affected in diffe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schlissel, Mark S., Durum, Scott D., Muegge, Kathrin
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2000
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193108/ https://www.ncbi.nlm.nih.gov/pubmed/10727465

Ejemplares similares

Interleukin 7 Receptor Control of T Cell Receptor γ Gene Rearrangement: Role of Receptor-associated Chains and Locus Accessibility
por: Durum, Scott K., et al.
Publicado: (1998)

The V–J Recombination of T Cell Receptor-γ Genes Is Blocked in Interleukin-7 Receptor–deficient Mice
por: Maki, Kazushige, et al.
Publicado: (1996)

Inhibition of Interleukin 7 Receptor Signaling by Antigen Receptor Assembly
por: Smart, Fiona M., et al.
Publicado: (2000)

Distinct Roles for Signals Relayed through the Common Cytokine Receptor γ Chain and Interleukin 7 Receptor α Chain in Natural T Cell Development
por: Boesteanu, Alina, et al.
Publicado: (1997)

Histone Acetylation Determines the Developmentally Regulated Accessibility for T Cell Receptor γ Gene Recombination
por: Agata, Yasutoshi, et al.
Publicado: (2001)

Loss of Bim Increases T Cell Production and Function in Interleukin 7 Receptor–deficient Mice
por: Pellegrini, Marc, et al.
Publicado: (2004)

Overlapping Roles of CXCL13, Interleukin 7 Receptor α, and CCR7 Ligands in Lymph Node Development
por: Luther, Sanjiv A., et al.
Publicado: (2003)

Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias
por: Shochat, Chen, et al.
Publicado: (2011)

Requirement of Tumor Necrosis Factor Receptor–Associated Factor (Traf)6 in Interleukin 17 Signal Transduction
por: Schwandner, Ralf, et al.
Publicado: (2000)

Plasmacytoid dendritic cell–specific receptor ILT7–FcɛRIγ inhibits Toll-like receptor–induced interferon production
por: Cao, Wei, et al.
Publicado: (2006)

Negative Signaling Pathways of the Killer Cell Inhibitory Receptor and FcγRIIb1 Require Distinct Phosphatases
por: Gupta, Neetu, et al.
Publicado: (1997)

Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
por: Seddiki, Nabila, et al.
Publicado: (2006)

The Major Receptor for C-Reactive Protein on Leukocytes Is Fcγ Receptor II
por: Bharadwaj, Dwaipayan, et al.
Publicado: (1999)

Changes in Locus-specific V(D)J Recombinase Activity Induced by Immunoglobulin Gene Products during B Cell Development
por: Constantinescu, Andrei, et al.
Publicado: (1997)

Interleukin 4 Reduces Expression of Inhibitory Receptors on B Cells and Abolishes CD22 and FcγRII-mediated B Cell Suppression
por: Rudge, Elizabeth U., et al.
Publicado: (2002)

Activating Fc γ receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies
por: Bulliard, Yannick, et al.
Publicado: (2013)

Interferon-α and Interleukin-12 Are Induced Differentially by Toll-like Receptor 7 Ligands in Human Blood Dendritic Cell Subsets
por: Ito, Tomoki, et al.
Publicado: (2002)

The miR-144/451 locus is required for erythroid homeostasis
por: Rasmussen, Kasper D., et al.
Publicado: (2010)

Interleukin 1 Receptor Dependence of Serum Transferred Arthritis Can be Circumvented by Toll-like Receptor 4 Signaling
por: Choe, Jung-Yoon, et al.
Publicado: (2003)

IL-7 Receptor Signals Inhibit Expression of Transcription Factors TCF-1, LEF-1, and RORγt: Impact on Thymocyte Development
por: Yu, Qing, et al.
Publicado: (2004)

Interferon γ Is Required for Activation-induced Death of T Lymphocytes
por: Refaeli, Yosef, et al.
Publicado: (2002)

Induction and Suppression of Collagen-Induced Arthritis Is Dependent on Distinct Fcγ Receptors
por: Kleinau, Sandra, et al.
Publicado: (2000)

C-reactive Protein: A Physiological Activator of Interleukin 6 Receptor Shedding
por: Jones, Simon A., et al.
Publicado: (1999)

Reversal of Proinflammatory Responses by Ligating the Macrophage Fcγ Receptor Type I
por: Sutterwala, Fayyaz S., et al.
Publicado: (1998)

Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9–driven antiinflammatory cytokine production
por: González-Navajas, Jose M., et al.
Publicado: (2010)

Paired Immunoglobulin-like Receptor (PIR)-A Is Involved in Activating Mast Cells through Its Association with Fc Receptor γ Chain
por: Maeda, Akito, et al.
Publicado: (1998)

Requirement of the Chemokine Receptor CXCR3 for Acute Allograft Rejection
por: Hancock, Wayne W., et al.
Publicado: (2000)

Requirement for the Chemokine Receptor Ccr6 in Allergic Pulmonary Inflammation
por: Lukacs, Nicholas W., et al.
Publicado: (2001)

Inducing Tumor Immunity through the Selective Engagement of Activating Fcγ Receptors on Dendritic Cells
por: Kalergis, Alexis M., et al.
Publicado: (2002)

Interleukin 12–dependent Interferon γ Production by CD8α(+)Lymphoid Dendritic Cells
por: Ohteki, Toshiaki, et al.
Publicado: (1999)

Interleukin 2 Signaling Is Required for CD4(+) Regulatory T Cell Function
por: Furtado, Gláucia C., et al.
Publicado: (2002)

Stimulation of Toll-like receptor 3 and 4 induces interleukin-1β maturation by caspase-8
por: Maelfait, Jonathan, et al.
Publicado: (2008)

T Cell–Independent Interleukin 15rα Signals Are Required for Bystander Proliferation
por: Lodolce, James P., et al.
Publicado: (2001)

The Interleukin 2 Receptor α Chain/CD25 Promoter Is a Target for Nuclear Factor of Activated T Cells
por: Schuh, Kai, et al.
Publicado: (1998)

Inhibition of Interleukin 1 Receptor/Toll-like Receptor Signaling through the Alternatively Spliced, Short Form of MyD88 Is Due to Its Failure to Recruit IRAK-4
por: Burns, Kimberly, et al.
Publicado: (2003)

The Scavenger Receptor MARCO Is Required for Lung Defense against Pneumococcal Pneumonia and Inhaled Particles
por: Arredouani, Mohamed, et al.
Publicado: (2004)

RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement
por: Lau, Christina M., et al.
Publicado: (2005)

Crystal Structure of the Human Natural Killer Cell Activating Receptor KIR2DS2 (CD158j)
por: Saulquin, Xavier, et al.
Publicado: (2003)

Human antibodies induce arthritis in mice deficient in the low-affinity inhibitory IgG receptor FcγRIIB
por: Petkova, Stefka B., et al.
Publicado: (2006)

The requirement for Notch signaling at the β-selection checkpoint in vivo is absolute and independent of the pre–T cell receptor
por: Maillard, Ivan, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_nrm0d6e2knv3dvejbhue1amflg