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Invariant Chain Controls H2-M Proteolysis in Mouse Splenocytes and Dendritic Cells
The association of invariant (Ii) chain with major histocompatibility complex (MHC) class II dimers is required for proper antigen presentation to T cells by antigen-presenting cells. Mice lacking Ii chain have severe abnormalities in class II transport, T cell selection, and B cell maturation. We d...
Autores principales: | Pierre, Philippe, Shachar, Idit, Matza, Didi, Gatti, Evelina, Flavell, Richard A., Mellman, Ira |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193111/ https://www.ncbi.nlm.nih.gov/pubmed/10727467 |
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