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An Essential Role for Thymic Mesenchyme in Early T Cell Development

We show that the mesenchymal cells that surround the 12-d mouse embryo thymus are necessary for T cell differentiation. Thus, epithelial lobes with attached mesenchyme generate all T cell populations in vitro, whereas lobes from which mesenchyme has been removed show poor lymphopoiesis with few cell...

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Detalles Bibliográficos
Autores principales:	Suniara, Ravinder K., Jenkinson, Eric J., Owen, John J.T.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2000
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193125/ https://www.ncbi.nlm.nih.gov/pubmed/10727466

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