Markedly Different Pathogenicity of Four Immunoglobulin G Isotype-Switch Variants of an Antierythrocyte Autoantibody Is Based on Their Capacity to Interact in Vivo with the Low-Affinity Fcγ Receptor III

Using three different Fcγ receptor (FcγR)-deficient mouse strains, we examined the induction of autoimmune hemolytic anemia by each of the four immunoglobulin (Ig)G isotype-switch variants of a 4C8 IgM antierythrocyte autoantibody and its relation to the contributions of the two FcγR, FcγRI, and Fcγ...

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Detalles Bibliográficos
Autores principales: Fossati-Jimack, Liliane, Ioan-Facsinay, Andreea, Reininger, Luc, Chicheportiche, Yves, Watanabe, Norihiko, Saito, Takashi, Hofhuis, Frans M. A., Gessner, J. Engelbert, Schiller, Carsten, Schmidt, Reinhold E., Honjo, Tasuku, Verbeek, J. Sjef, Izui, Shozo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193130/
https://www.ncbi.nlm.nih.gov/pubmed/10770797

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