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The Role of Virus-Specific Cd8(+) Cells in Liver Damage and Viral Control during Persistent Hepatitis B Virus Infection
Hepatitis B virus (HBV) is a noncytopathic virus, and the recognition of infected hepatocytes by HBV-specific CD8 cells has been assumed to be the central mechanism causing both liver damage and virus control. To understand the role of cytotoxic T cells in the pathogenesis of HBV infection, we used...
Autores principales: | Maini, Mala K., Boni, Carolina, Lee, Chun Kyon, Larrubia, Juan R., Reignat, Stephanie, Ogg, Graham S., King, Abigail S., Herberg, Jethro, Gilson, Richard, Alisa, Akeem, Williams, Roger, Vergani, Diego, Naoumov, Nikolai V., Ferrari, Carlo, Bertoletti, Antonio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193131/ https://www.ncbi.nlm.nih.gov/pubmed/10770795 |
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