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Entry of B Cell Receptor into Signaling Domains Is Inhibited in Tolerant B Cells
Signal transduction through the B cell antigen receptor (BCR) is altered in B cells that express a receptor that recognizes self-antigen. To understand the molecular basis for the change in signaling in autoreactive B cells, a transgenic model was used to isolate a homogeneous population of tolerant...
Autores principales: | Weintraub, Bennett C., Jun, Jesse Eunsuk, Bishop, Anthony C., Shokat, Kevan M., Thomas, Matthew L., Goodnow, Christopher C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193133/ https://www.ncbi.nlm.nih.gov/pubmed/10770810 |
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