Bruton's Tyrosine Kinase Links the B Cell Receptor to Nuclear Factor κb Activation

The recognition of antigen by membrane immunoglobulin M (mIgM) results in a complex series of signaling events in the cytoplasm leading to gene activation. Bruton's tyrosine kinase (BTK), a member of the Tec family of tyrosine kinases, is essential for the full repertoire of IgM signals to be t...

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Detalles Bibliográficos
Autores principales: Bajpai, Urmila D., Zhang, Keming, Teutsch, Mark, Sen, Ranjan, Wortis, Henry H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193152/
https://www.ncbi.nlm.nih.gov/pubmed/10811866

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