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Human Cd4(+) T Lymphocytes Consistently Respond to the Latent Epstein-Barr Virus Nuclear Antigen Ebna1
The Epstein-Barr virus (EBV)-encoded nuclear antigen EBNA1 is critical for the persistence of the viral episome in replicating EBV-transformed human B cells. Therefore, all EBV-induced tumors express this foreign antigen. However, EBNA1 is invisible to CD8(+) cytotoxic T lymphocytes because its Gly/...
Autores principales: | Münz, Christian, Bickham, Kara L., Subklewe, Marion, Tsang, Ming L., Chahroudi, Ann, Kurilla, Michael G., Zhang, Dan, O'Donnell, Michael, Steinman, Ralph M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193162/ https://www.ncbi.nlm.nih.gov/pubmed/10811859 |
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