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Role for Cathepsin F in Invariant Chain Processing and Major Histocompatibility Complex Class II Peptide Loading by Macrophages
The major histocompatibility complex (MHC) class II–associated invariant chain (Ii) regulates intracellular trafficking and peptide loading of MHC class II molecules. Such loading occurs after endosomal degradation of the invariant chain to a ∼3-kD peptide termed CLIP (class II–associated invariant...
Autores principales: | Shi, Guo-Ping, Bryant, Rebecca A.R., Riese, Richard, Verhelst, Steven, Driessen, Christoph, Li, Zhenqiang, Bromme, Dieter, Ploegh, Hidde L., Chapman, Harold A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193169/ https://www.ncbi.nlm.nih.gov/pubmed/10748235 |
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