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Notch1 Deficiency Dissociates the Intrathymic Development of Dendritic Cells and T Cells
Thymic dendritic cells (DCs) form a discrete subset of bone marrow (BM)-derived cells, the function of which is to mediate negative selection of autoreactive thymocytes. The developmental origin of thymic DCs remains controversial. Although cell transfer studies support a model in which T cells and...
Autores principales: | Radtke, Freddy, Ferrero, Isabel, Wilson, Anne, Lees, Rosemary, Aguet, Michel, MacDonald, H. Robson |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193172/ https://www.ncbi.nlm.nih.gov/pubmed/10748227 |
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