Extracellular K(+) and Opening of Voltage-Gated Potassium Channels Activate T Cell Integrin Function: Physical and Functional Association between Kv1.3 Channels and β1 Integrins

Elevated extracellular K(+) ([K(+)](o)), in the absence of “classical” immunological stimulatory signals, was found to itself be a sufficient stimulus to activate T cell β1 integrin moieties, and to induce integrin-mediated adhesion and migration. Gating of T cell voltage-gated K(+) channels (Kv1.3)...

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Detalles Bibliográficos
Autores principales: Levite, Mia, Cahalon, Liora, Peretz, Asher, Hershkoviz, Rami, Sobko, Alex, Ariel, Amiram, Desai, Rooma, Attali, Bernard, Lider, Ofer
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193178/
https://www.ncbi.nlm.nih.gov/pubmed/10748234

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