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Targeted Disruption of the Leukotriene B(4)Receptor in Mice Reveals Its Role in Inflammation and Platelet-Activating Factor–Induced Anaphylaxis

Leukotrienes are derived from arachidonic acid and serve as mediators of inflammation and immediate hypersensitivity. Leukotriene B(4) (LTB(4)) and leukotriene C(4) (LTC(4)) act through G protein–coupled receptors LTB(4) receptor (BLTR) and Cys-LTR, respectively. To investigate the physiological rol...

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Detalles Bibliográficos
Autores principales: Haribabu, Bodduluri, Verghese, Margrith W., Steeber, Douglas A., Sellars, Dwight D., Bock, Cheryl B., Snyderman, Ralph
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193219/
https://www.ncbi.nlm.nih.gov/pubmed/10934231