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Targeted Disruption of the Leukotriene B(4)Receptor in Mice Reveals Its Role in Inflammation and Platelet-Activating Factor–Induced Anaphylaxis
Leukotrienes are derived from arachidonic acid and serve as mediators of inflammation and immediate hypersensitivity. Leukotriene B(4) (LTB(4)) and leukotriene C(4) (LTC(4)) act through G protein–coupled receptors LTB(4) receptor (BLTR) and Cys-LTR, respectively. To investigate the physiological rol...
Autores principales: | Haribabu, Bodduluri, Verghese, Margrith W., Steeber, Douglas A., Sellars, Dwight D., Bock, Cheryl B., Snyderman, Ralph |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193219/ https://www.ncbi.nlm.nih.gov/pubmed/10934231 |
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