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A NASP (N1/N2)-Related Protein, Sim3, Binds CENP-A and Is Required for Its Deposition at Fission Yeast Centromeres

A defining feature of centromeres is the presence of the histone H3 variant CENP-A(Cnp1). It is not known how CENP-A(Cnp1) is specifically delivered to, and assembled into, centromeric chromatin. Through a screen for factors involved in kinetochore integrity in fission yeast, we identified Sim3. Sim...

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Detalles Bibliográficos
Autores principales:	Dunleavy, Elaine M., Pidoux, Alison L., Monet, Marie, Bonilla, Carolina, Richardson, William, Hamilton, Georgina L., Ekwall, Karl, McLaughlin, Paul J., Allshire, Robin C.
Formato:	Texto
Lenguaje:	English
Publicado:	Cell Press 2007
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193228/ https://www.ncbi.nlm.nih.gov/pubmed/18158900 http://dx.doi.org/10.1016/j.molcel.2007.10.010

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