Osteoprotegerin Reverses Osteoporosis by Inhibiting Endosteal Osteoclasts and Prevents Vascular Calcification by Blocking a Process Resembling Osteoclastogenesis

High systemic levels of osteoprotegerin (OPG) in OPG transgenic mice cause osteopetrosis with normal tooth eruption and bone elongation and inhibit the development and activity of endosteal, but not periosteal, osteoclasts. We demonstrate that both intravenous injection of recombinant OPG protein an...

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Detalles Bibliográficos
Autores principales: Min, Hosung, Morony, Sean, Sarosi, Ildiko, Dunstan, Colin R., Capparelli, Casey, Scully, Sheila, Van, Gwyneth, Kaufman, Steve, Kostenuik, Paul J., Lacey, David L., Boyle, William J., Simonet, W. Scott
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193236/
https://www.ncbi.nlm.nih.gov/pubmed/10952716

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