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Ras Mediates Effector Pathways Responsible for Pre-B Cell Survival, Which Is Essential for the Developmental Progression to the Late Pre-B Cell Stage
Ras is essential for the transition from early B cell precursors to the pro-B stage, and is considered to be involved in the signal cascade mediated by pre-B cell antigen receptors. To examine the role of p21(ras) in the late stage of B cell differentiation, we established transgenic mice (TG) expre...
Autores principales: | Nagaoka, Hitoshi, Takahashi, Yoshimasa, Hayashi, Reiko, Nakamura, Tohru, Ishii, Kumiko, Matsuda, Junichiro, Ogura, Atsuo, Shirakata, Yumiko, Karasuyama, Hajime, Sudo, Tetsuo, Nishikawa, Shin-Ichi, Tsubata, Takeshi, Mizuochi, Tsuguo, Asano, Toshihiko, Sakano, Hitoshi, Takemori, Toshitada |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193247/ https://www.ncbi.nlm.nih.gov/pubmed/10899904 |
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