Salmonella Exploits Caspase-1 to Colonize Peyer's Patches in a Murine Typhoid Model

Salmonella typhimurium invades host macrophages and induces apoptosis and the release of mature proinflammatory cytokines. SipB, a protein translocated by Salmonella into the cytoplasm of macrophages, is required for activation of Caspase-1 (Casp-1, an interleukin [IL]-1β–converting enzyme), which i...

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Detalles Bibliográficos
Autores principales: Monack, Denise M., Hersh, David, Ghori, Nafisa, Bouley, Donna, Zychlinsky, Arturo, Falkow, Stanley
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193260/
https://www.ncbi.nlm.nih.gov/pubmed/10899911

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