Overexpression of Acid Ceramidase Protects from Tumor Necrosis Factor–Induced Cell Death

Tumor necrosis factor (TNF) signals cell death and simultaneously induces generation of ceramide. To evaluate the contribution of ceramide to TNF-dependent cell death, we generated clones of the TNF-sensitive cell line L929 that constitutively overexpress human acid ceramidase (AC). Ceramidase, in c...

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Detalles Bibliográficos
Autores principales: Strelow, Astrid, Bernardo, Katussevani, Adam-Klages, Sabine, Linke, Thomas, Sandhoff, Konrad, Krönke, Martin, Adam, Dieter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193270/
https://www.ncbi.nlm.nih.gov/pubmed/10974027

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