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Akt-Dependent Cytokine Production in Mast Cells
Cross-linking of FcεRI induces the activation of three protein tyrosine kinases, Lyn, Syk, and Bruton's tyrosine kinase (Btk), leading to the secretion of a panel of proinflammatory mediators from mast cells. This study showed phosphorylation at Ser-473 and enzymatic activation of Akt/protein k...
Autores principales: | Kitaura, Jiro, Asai, Koichi, Maeda-Yamamoto, Mari, Kawakami, Yuko, Kikkawa, Ushio, Kawakami, Toshiaki |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193272/ https://www.ncbi.nlm.nih.gov/pubmed/10974038 |
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