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Interleukin (Il)-4 Is a Major Regulatory Cytokine Governing Bioactive IL-12 Production by Mouse and Human Dendritic Cells

Interleukin (IL)-12 may be secreted as a bioactive T helper type 1 (Th1) cell–inducing heterodimer, as a monomer, or as an antagonistic homodimer. We analyzed the IL-12 produced by mouse splenic dendritic cells (DCs), human thymic DCs, and cultured human monocyte-derived DCs. IL-12 production requir...

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Detalles Bibliográficos
Autores principales:	Hochrein, Hubertus, O'Keeffe, Meredith, Luft, Thomas, Vandenabeele, Stéphane, Grumont, Raelene J., Maraskovsky, Eugene, Shortman, Ken
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2000
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193283/ https://www.ncbi.nlm.nih.gov/pubmed/10993913

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