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Function of Cd3ε-Mediated Signals in T Cell Development

The T cell antigen receptor (TCR) and pre-TCR complexes are composed of multiple signal-transducing subunits (CD3γ, CD3δ, CD3ε, and ζ) that each contain one or more copies of a semiconserved functional motif, the immunoreceptor tyrosine-based activation motif (ITAM). Although biochemical studies ind...

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Detalles Bibliográficos
Autores principales:	Sommers, Connie L., Dejarnette, Jan B., Huang, Kun, Lee, Jan, El-Khoury, Dalal, Shores, Elizabeth W., Love, Paul E.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2000
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193290/ https://www.ncbi.nlm.nih.gov/pubmed/10993922

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