Cargando…

Nitric Oxide–Dependent Activation of P53 Suppresses Bleomycin-Induced Apoptosis in the Lung

Chronic inflammation leading to pulmonary fibrosis develops in response to environmental pollutants, radiotherapy, or certain cancer chemotherapeutic agents. We speculated that lung injury might be mediated by p53, a proapoptotic transcription factor widely implicated in the response of cells to DNA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Davis, Darren W., Weidner, Douglas A., Holian, Andrij, McConkey, David J.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2000
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193293/ https://www.ncbi.nlm.nih.gov/pubmed/10993916

Ejemplares similares

The Effect of Size on Ag Nanosphere Toxicity in Macrophage Cell Models and Lung Epithelial Cell Lines Is Dependent on Particle Dissolution
por: Hamilton, Raymond F., et al.
Publicado: (2014)

Inhibition or knock out of Inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury
por: Genovese, Tiziana, et al.
Publicado: (2005)

Calycosin Ameliorates Bleomycin-Induced Pulmonary Fibrosis via Suppressing Oxidative Stress, Apoptosis, and Enhancing Autophagy
por: Liu, Haoge, et al.
Publicado: (2022)

Nitric oxide exerts protective effects against bleomycin-induced pulmonary fibrosis in mice
por: Noguchi, Shingo, et al.
Publicado: (2014)

Macrophage fusion caused by particle instillation
por: Trout, Kevin L., et al.
Publicado: (2020)

Particle length-dependent titanium dioxide nanomaterials toxicity and bioactivity
por: Hamilton, Raymond F, et al.
Publicado: (2009)

Contribution of Particle-Induced Lysosomal Membrane Hyperpolarization to Lysosomal Membrane Permeabilization
por: Ziglari, Tahereh, et al.
Publicado: (2021)

Effect of MWCNT size, carboxylation, and purification on in vitro and in vivo toxicity, inflammation and lung pathology
por: Hamilton, Raymond F, et al.
Publicado: (2013)

Potential Role of the Inflammasome-Derived Inflammatory Cytokines in Pulmonary Fibrosis
por: Biswas, Rupa, et al.
Publicado: (2011)

Role of Lysosomes in Silica-Induced Inflammasome Activation and Inflammation in Absence of MARCO
por: Biswas, Rupa, et al.
Publicado: (2014)

Immunological Effects of Environmental Factors: Focus on the Fibrous and Particulated Materials
por: Otsuki, Takemi, et al.
Publicado: (2014)

Oxygen dependence of nitric oxide-mediated signaling()
por: Hickok, Jason R., et al.
Publicado: (2013)

A comparison of dispersing media for various engineered carbon nanoparticles
por: Buford, Mary C, et al.
Publicado: (2007)

Cholesterol content regulates silica-induced lysosomal membrane permeability
por: Sydor, Matthew J., et al.
Publicado: (2023)

Autophagy is required for crizotinib-induced apoptosis in MET-amplified gastric cancer cells
por: Schroeder, Rebecca D., et al.
Publicado: (2017)

Gas6 Ameliorates Inflammatory Response and Apoptosis in Bleomycin-Induced Acute Lung Injury
por: Kim, Bo-Min, et al.
Publicado: (2021)

The Effects of Varying Degree of MWCNT Carboxylation on Bioactivity in Various In Vivo and In Vitro Exposure Models
por: Hamilton, Raymond F., et al.
Publicado: (2018)

Editorial: Inorganic particles and fibres: integrating minero-chemistry and hazard assessment for eco-exposome development
por: Petriglieri, Jasmine Rita, et al.
Publicado: (2023)

siRNA-mediated targeting of the RNA-dependent RNA polymerase in the Norovirus genome
por: Mac Cann, Rachel, et al.
Publicado: (2015)

Nitric oxide-dependent anaerobic ammonium oxidation
por: Hu, Ziye, et al.
Publicado: (2019)

Inhibition of endocytosis suppresses the nitric oxide-dependent release of Cl(-) in retinal amacrine cells
por: Dunn, Vernon K., et al.
Publicado: (2018)

Suppression of arthritis by an inhibitor of nitric oxide synthase
Publicado: (1993)

Nitric oxide suppresses cilia activity in ctenophores
por: Norekian, Tigran P., et al.
Publicado: (2023)

Osteopontin regulates proliferation, apoptosis, and migration of murine claudin-low mammary tumor cells
por: Saleh, S., et al.
Publicado: (2016)

Bleomycin: Lung toxicity: case report
Publicado: (2021)

A Brief Measure of Parental Wellbeing for Use in Evaluations of Family-Centred Interventions for Children with Developmental Disabilities
por: McConkey, Roy
Publicado: (2020)

Responding to Autism in Low and Middle Income Countries (Lmic): What to Do and What Not to Do
por: McConkey, Roy
Publicado: (2022)

Nonpulmonary Outcomes of Asbestos Exposure
por: Bunderson-Schelvan, Melisa, et al.
Publicado: (2011)

Nitric Oxide-Induced Apoptosis of Human Dental Pulp Cells Is Mediated by the Mitochondria-Dependent Pathway
por: Park, Min Young, et al.
Publicado: (2014)

Nitric oxide-mediated apoptosis of neutrophils through caspase-8 and caspase-3-dependent mechanism
por: Dubey, Megha, et al.
Publicado: (2016)

Nitric oxide inhibits endothelial cell apoptosis by inhibiting cysteine‐dependent SOD1 monomerization
por: Peng, Hanlin, et al.
Publicado: (2022)

Bleomycin Sensitivity in Escherichia coli is Medium-Dependent
por: Xu, Tao, et al.
Publicado: (2012)

Periostin antisense oligonucleotide suppresses bleomycin‐induced formation of a lung premetastatic niche for melanoma
por: Semba, Takashi, et al.
Publicado: (2018)

Downregulation of PTEN mediates bleomycin-induced premature senescence in lung cancer cells by suppressing autophagy
por: Sai, Xiaoyan, et al.
Publicado: (2020)

Nitric oxide and its congeners in mitochondria: implications for apoptosis.
por: Richter, C
Publicado: (1998)

Vascular endothelial growth factor and nitric oxide synthase expression in human lung cancer and the relation to p53.
por: Ambs, S., et al.
Publicado: (1998)

Significant Correlation of Nitric Oxide Synthase Activity and p53 Gene Mutation in Stage I Lung Adenocarcinoma
por: Fujimoto, Hisao, et al.
Publicado: (1998)

Hsp90β inhibition modulates nitric oxide production and nitric oxide-induced apoptosis in human chondrocytes
por: Calamia, Valentina, et al.
Publicado: (2011)

Effect of Carbon Nanotube-Metal Hybrid Particle Exposure to Freshwater Algae Chlamydomonas reinhardtii
por: Intrchom, Worawit, et al.
Publicado: (2018)

Silica Triggers Inflammation and Ectopic Lymphoid Neogenesis in the Lungs in Parallel with Accelerated Onset of Systemic Autoimmunity and Glomerulonephritis in the Lupus-Prone NZBWF1 Mouse
por: Bates, Melissa A., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_f79ru4dmq5l5vfl9m9ocrfi1u9