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Functional Dichotomy in Natural Killer Cell Signaling: Vav1-Dependent and -Independent Mechanisms

The product of the protooncogene Vav1 participates in multiple signaling pathways and is a critical regulator of antigen–receptor signaling in B and T lymphocytes, but its role during in vivo natural killer (NK) cell differentiation is not known. Here we have studied NK cell development in Vav1 (−)...

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Detalles Bibliográficos
Autores principales: Colucci, Francesco, Rosmaraki, Eleftheria, Bregenholt, Søren, Samson, Sandrine I., Di Bartolo, Vincenzo, Turner, Martin, Vanes, Lesley, Tybulewicz, Victor, Di Santo, James P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193296/
https://www.ncbi.nlm.nih.gov/pubmed/11413196