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Essential Requirement for C-KIT and Common γ Chain in Thymocyte Development Cannot Be Overruled by Enforced Expression of Bcl-2

The thymus in mice lacking both the receptor tyrosine kinase c-kit and the common cytokine receptor γ chain (γ(c)) is alymphoid because these receptors provide essential signals at the earliest stages of thymocyte development. The signals transduced by these receptors potentially regulate proliferat...

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Detalles Bibliográficos
Autores principales: Rodewald, Hans-Reimer, Waskow, Claudia, Haller, Corinne
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193302/
https://www.ncbi.nlm.nih.gov/pubmed/11413198