Dynamic Tuning of T Cell Reactivity by Self-Peptide–Major Histocompatibility Complex Ligands

Intrathymic self-peptide–major histocompatibility complex class II (MHC) molecules shape the T cell repertoire through positive and negative selection of immature CD4(+)CD8(+) thymocytes. By analyzing the development of MHC class II–restricted T cell receptor (TCR) transgenic T cells under condition...

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Detalles Bibliográficos
Autores principales: Wong, Phillip, Barton, Gregory M., Forbush, Katherine A., Rudensky, Alexander Y.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193333/
https://www.ncbi.nlm.nih.gov/pubmed/11369789

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