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The μ Switch Region Tandem Repeats Are Important, but Not Required, for Antibody Class Switch Recombination

Class switch DNA recombinations change the constant (C) region of the antibody heavy (H) chain expressed by a B cell and thereby change the antibody effector function. Unusual tandemly repeated sequence elements located upstream of H chain gene exons have long been thought to be important in the tar...

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Detalles Bibliográficos
Autores principales: Luby, Thomas M., Schrader, Carol E., Stavnezer, Janet, Selsing, Erik
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193334/
https://www.ncbi.nlm.nih.gov/pubmed/11148220