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The μ Switch Region Tandem Repeats Are Important, but Not Required, for Antibody Class Switch Recombination
Class switch DNA recombinations change the constant (C) region of the antibody heavy (H) chain expressed by a B cell and thereby change the antibody effector function. Unusual tandemly repeated sequence elements located upstream of H chain gene exons have long been thought to be important in the tar...
Autores principales: | Luby, Thomas M., Schrader, Carol E., Stavnezer, Janet, Selsing, Erik |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193334/ https://www.ncbi.nlm.nih.gov/pubmed/11148220 |
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