Caspase Activation Is Required for Terminal Erythroid Differentiation

The cysteine proteases known as caspases play a central role in most apoptotic pathways. Here, we show that caspase inhibitors arrest the maturation of human erythroid progenitors at early stages of differentiation, before nucleus and chromatin condensation. Effector caspases such as caspase-3 are t...

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Detalles Bibliográficos
Autores principales: Zermati, Yael, Garrido, Carmen, Amsellem, Sophie, Fishelson, Serge, Bouscary, Didier, Valensi, Françoise, Varet, Bruno, Solary, Eric, Hermine, Olivier
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193347/
https://www.ncbi.nlm.nih.gov/pubmed/11208865

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