Natural Resistance to Intracellular Infections: Natural Resistance–Associated Macrophage Protein 1 (Nramp1) Functions as a Ph-Dependent Manganese Transporter at the Phagosomal Membrane

Mutations at the natural resistance–associated macrophage protein 1 (Nramp1) locus cause susceptibility to infection with antigenically unrelated intracellular pathogens. Nramp1 codes for an integral membrane protein expressed in the lysosomal compartment of macrophages, and is recruited to the memb...

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Detalles Bibliográficos
Autores principales: Jabado, Nada, Jankowski, Andrzej, Dougaparsad, Samuel, Picard, Virginie, Grinstein, Sergio, Gros, Philippe
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193348/
https://www.ncbi.nlm.nih.gov/pubmed/11067873

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