Cargando…
C-Reactive Protein Binds to Apoptotic Cells, Protects the Cells from Assembly of the Terminal Complement Components, and Sustains an Antiinflammatory Innate Immune Response: Implications for Systemic Autoimmunity
C-reactive protein (CRP) is a serum protein that is massively induced as part of the innate immune response to infection and tissue injury. As CRP has been detected in damaged tissues and is known to activate complement, we assessed whether apoptotic lymphocytes bound CRP and determined the effect o...
Autores principales: | Gershov, Debra, Kim, SunJung, Brot, Nathan, Elkon, Keith B. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193350/ https://www.ncbi.nlm.nih.gov/pubmed/11067883 |
Ejemplares similares
-
Complement-dependent Clearance of Apoptotic Cells by Human Macrophages
por: Mevorach, Dror, et al.
Publicado: (1998) -
I-PLA(2) Activation during Apoptosis Promotes the Exposure of Membrane Lysophosphatidylcholine Leading to Binding by Natural Immunoglobulin M Antibodies and Complement Activation
por: Kim, Sun Jun, et al.
Publicado: (2002) -
SIRT1 inactivation switches reactive astrocytes to an antiinflammatory phenotype in CNS autoimmunity
por: Zhang, Weifeng, et al.
Publicado: (2022) -
Complement, its role in innate immunity and autoimmunity
por: Daha, M
Publicado: (2003) -
Antiinflammatory eggs
por: Powell, Kendall
Publicado: (2005)