Cargando…
The Notch Ligand Jagged-1 Represents a Novel Growth Factor of Human Hematopoietic Stem Cells
The Notch ligand, Jagged-1, plays an essential role in tissue formation during embryonic development of primitive organisms. However, little is known regarding the role of Jagged-1 in the regulation of tissue-specific stem cells or its function in humans. Here, we show that uncommitted human hematop...
Autores principales: | Karanu, Frances N., Murdoch, Barbara, Gallacher, Lisa, Wu, Dongmei M., Koremoto, Masahide, Sakano, Seiji, Bhatia, Mickie |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193352/ https://www.ncbi.nlm.nih.gov/pubmed/11067884 |
Ejemplares similares
-
Quantitative Analysis Reveals Expansion of Human Hematopoietic Repopulating Cells After Short-term Ex Vivo Culture
por: Bhatia, Mickie, et al.
Publicado: (1997) -
Density of the Notch ligand Delta1 determines generation of B and T cell precursors from hematopoietic stem cells
por: Dallas, Mari H., et al.
Publicado: (2005) -
Bone Morphogenetic Proteins Regulate the Developmental Program of Human Hematopoietic Stem Cells
por: Bhatia, Mickie, et al.
Publicado: (1999) -
Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment
por: Koch, Ute, et al.
Publicado: (2008) -
NOTCH ligands JAG1 and JAG2 as critical pro-survival factors in childhood medulloblastoma
por: Fiaschetti, Giulio, et al.
Publicado: (2014)