Immunosuppression and Resultant Viral Persistence by Specific Viral Targeting of Dendritic Cells

Among cells of the immune system, CD11c(+) and DEC-205(+) splenic dendritic cells primarily express the cellular receptor (α-dystroglycan [α-DG]) for lymphocytic choriomeningitis virus (LCMV). By selection, strains and variants of LCMV that bind α-DG with high affinity are associated with virus repl...

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Detalles Bibliográficos
Autores principales: Sevilla, Noemí, Kunz, Stefan, Holz, Andreas, Lewicki, Hanna, Homann, Dirk, Yamada, Hiroki, Campbell, Kevin P., de la Torre, Juan C., Oldstone, Michael B.A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193355/
https://www.ncbi.nlm.nih.gov/pubmed/11067874

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