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Inhibition of T1/St2 during Respiratory Syncytial Virus Infection Prevents T Helper Cell Type 2 (Th2)- but Not Th1-Driven Immunopathology
T cells secreting interleukin (IL)-4 and IL-5 (T helper cell type 2 [Th2] cells) play a detrimental role in a variety of diseases, but specific methods of regulating their activity remain elusive. T1/ST2 is a surface ligand of the IL-1 receptor family, expressed on Th2- but not on interferon (IFN)-γ...
Autores principales: | Walzl, Gerhard, Matthews, Stephen, Kendall, Sharon, Gutierrez-Ramos, Jose Carlos, Coyle, Anthony J., Openshaw, Peter J.M., Hussell, Tracy |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193366/ https://www.ncbi.nlm.nih.gov/pubmed/11283151 |
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