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Inhibition of T1/St2 during Respiratory Syncytial Virus Infection Prevents T Helper Cell Type 2 (Th2)- but Not Th1-Driven Immunopathology

T cells secreting interleukin (IL)-4 and IL-5 (T helper cell type 2 [Th2] cells) play a detrimental role in a variety of diseases, but specific methods of regulating their activity remain elusive. T1/ST2 is a surface ligand of the IL-1 receptor family, expressed on Th2- but not on interferon (IFN)-γ...

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Detalles Bibliográficos
Autores principales: Walzl, Gerhard, Matthews, Stephen, Kendall, Sharon, Gutierrez-Ramos, Jose Carlos, Coyle, Anthony J., Openshaw, Peter J.M., Hussell, Tracy
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193366/
https://www.ncbi.nlm.nih.gov/pubmed/11283151

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