Matrix Metalloproteinase 9 Protects Mice from Anti–Glomerular Basement Membrane Nephritis through Its Fibrinolytic Activity

Matrix metalloproteinase (MMP)9/gelatinase B is increased in various nephropathies. To investigate its role, we used a genetic approach. Adult MMP9-deficient (MMP9(−/)−) mice showed normal renal histology and function at 3 mo. We investigated the susceptibility of 3-mo-old mice to the accelerated mo...

Descripción completa

Detalles Bibliográficos
Autores principales: Lelongt, Brigitte, Bengatta, Soraya, Delauche, Madeleine, Lund, Leif R., Werb, Zena, Ronco, Pierre M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193369/
https://www.ncbi.nlm.nih.gov/pubmed/11283152

Ejemplares similares

Ejemplares similares