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A Critical Role for Lymphotoxin-β Receptor in the Development of Diabetes in Nonobese Diabetic Mice
To assess the role of lymphotoxin-β receptor (LTβR) in diabetes pathogenesis, we expressed an LTβR–Fc fusion protein in nonobese diabetic (NOD) mice. The fusion protein was expressed in the embryo, reached high levels for the first 2 wk after birth, and then declined progressively with age. High exp...
Autores principales: | Ettinger, Rachel, Munson, Sibyl H., Chao, Cheng-Chi, Vadeboncoeur, Mary, Toma, Jon, McDevitt, Hugh O. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193386/ https://www.ncbi.nlm.nih.gov/pubmed/11390441 |
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