Cargando…
Essential Role of Nuclear Factor (NF)-κB–Inducing Kinase and Inhibitor of κb (Iκb) Kinase α in Nf-κb Activation through Lymphotoxin β Receptor, but Not through Tumor Necrosis Factor Receptor I
Both nuclear factor (NF)-κB–inducing kinase (NIK) and inhibitor of κB (IκB) kinase (IKK) have been implicated as essential components for NF-κB activation in response to many external stimuli. However, the exact roles of NIK and IKKα in cytokine signaling still remain controversial. With the use of...
Autores principales: | Matsushima, Akemi, Kaisho, Tsuneyasu, Rennert, Paul D., Nakano, Hiroyasu, Kurosawa, Kyoko, Uchida, Daisuke, Takeda, Kiyoshi, Akira, Shizuo, Matsumoto, Mitsuru |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193391/ https://www.ncbi.nlm.nih.gov/pubmed/11238593 |
Ejemplares similares
-
Iκb Kinase α Is Essential for Mature B Cell Development and Function
por: Kaisho, Tsuneyasu, et al.
Publicado: (2001) -
PDLIM1 inhibits NF-κB-mediated inflammatory signaling by sequestering the p65 subunit of NF-κB in the cytoplasm
por: Ono, Rumiko, et al.
Publicado: (2015) -
Protein Kinase C β Controls Nuclear Factor κB Activation in B Cells Through Selective Regulation of the IκB Kinase α
por: Saijo, Kaoru, et al.
Publicado: (2002) -
Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia
por: Mansouri, Larry, et al.
Publicado: (2015) -
Beyond NF-κB activation: nuclear functions of IκB kinase α
por: Huang, Wei-Chien, et al.
Publicado: (2013)