Cargando…
Induction of a Diverse T Cell Receptor γ/δ Repertoire by the Helix-Loop-Helix Proteins E2a and Heb in Nonlymphoid Cells
During specific stages of thymocyte development, the T cell receptor (TCR) locus is assembled from variable (V), diversity (D), and joining (J) gene segments. Proper TCR γ and δ V(D)J rearrangement during thymocyte development requires the presence of the E2A proteins. Here we show that E2A and a cl...
Autores principales: | Ghosh, Jimut Kanti, Romanow, William J., Murre, Cornelis |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193417/ https://www.ncbi.nlm.nih.gov/pubmed/11257142 |
Ejemplares similares
-
Helix-Loop-Helix Proteins in Adaptive Immune Development
por: Aubrey, Megan, et al.
Publicado: (2022) -
Helix–loop–helix proteins and the advent of cellular diversity: 30 years of discovery
por: Murre, Cornelis
Publicado: (2019) -
Induction of Early B Cell Factor (EBF) and Multiple B Lineage Genes by the Basic Helix-Loop-Helix Transcription Factor E12
por: Kee, Barbara L., et al.
Publicado: (1998) -
Inhibition of T Cell and Promotion of Natural Killer Cell Development by the Dominant Negative Helix Loop Helix Factor Id3
por: Heemskerk, Mirjam H.M., et al.
Publicado: (1997) -
Thymocyte Maturation Is Regulated by the Activity of the Helix-Loop-Helix Protein, E47
por: Bain, Gretchen, et al.
Publicado: (1999)