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Staphylococcus aureus Resistance to Human Defensins and Evasion of Neutrophil Killing via the Novel Virulence Factor Mprf Is Based on Modification of Membrane Lipids with l-Lysine
Defensins, antimicrobial peptides of the innate immune system, protect human mucosal epithelia and skin against microbial infections and are produced in large amounts by neutrophils. The bacterial pathogen Staphylococcus aureus is insensitive to defensins by virtue of an unknown resistance mechanism...
Autores principales: | Peschel, Andreas, Jack, Ralph W., Otto, Michael, Collins, L. Vincent, Staubitz, Petra, Nicholson, Graeme, Kalbacher, Hubert, Nieuwenhuizen, Willem F., Jung, Günther, Tarkowski, Andrej, van Kessel, Kok P.M., van Strijp, Jos A.G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193429/ https://www.ncbi.nlm.nih.gov/pubmed/11342591 |
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