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Increased Severity of Local and Systemic Anaphylactic Reactions in Gp49b1-Deficient Mice

gp49B1 is an immunoglobulin (Ig) superfamily member that inhibits FcεRI-induced mast cell activation when the two receptors are coligated with antibodies in vitro. The critical question of in vivo function of gp49B1 is now addressed in gene-disrupted mice. gp49B1-deficient mice exhibited a significa...

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Detalles Bibliográficos
Autores principales: Daheshia, Massoud, Friend, Daniel S., Grusby, Michael J., Austen, K. Frank, Katz, Howard R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193448/
https://www.ncbi.nlm.nih.gov/pubmed/11457897