Inactivation of Lrg-47 and Irg-47 Reveals a Family of Interferon γ–Inducible Genes with Essential, Pathogen-Specific Roles in Resistance to Infection

The cytokine interferon (IFN)-γ regulates immune clearance of parasitic, bacterial, and viral infections; however, the underlying mechanisms are poorly understood. Recently, a family of IFN-γ–induced genes has been identified that encode 48-kD GTP-binding proteins that localize to the endoplasmic re...

Descripción completa

Detalles Bibliográficos
Autores principales: Collazo, Carmen M., Yap, George S., Sempowski, Gregory D., Lusby, Kimberly C., Tessarollo, Lino, Woude, George F. Vande, Sher, Alan, Taylor, Gregory A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193451/
https://www.ncbi.nlm.nih.gov/pubmed/11457893

Ejemplares similares

Ejemplares similares