FAS Ligand Triggers Pulmonary Silicosis

We investigated the role of Fas ligand in murine silicosis. Wild-type mice instilled with silica developed severe pulmonary inflammation, with local production of tumor necrosis factor (TNF)-α, and interstitial neutrophil and macrophage infiltration in the lungs. Strikingly, Fas ligand–deficient gen...

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Detalles Bibliográficos
Autores principales: Borges, Valéria M., Falcão, Haroldo, Leite-Júnior, José H., Alvim, Luciana, Teixeira, Gerlinde P., Russo, Momtchilo, Nóbrega, Alberto F., Lopes, Marcela F., Rocco, Patricia M., Davidson, Wendy F., Linden, Rafael, Yagita, Hideo, Zin, Walter A., DosReis, George A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193452/
https://www.ncbi.nlm.nih.gov/pubmed/11457890

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