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Interferon γ Stabilizes the T Helper Cell Type 1 Phenotype

T helper cell (Th)1-primed CD4 T cells from wild-type donors make little interleukin (IL)-4 when restimulated under Th2 conditions. However, such restimulation of Th1-primed cells from interferon (IFN)-γ(2/−) or IFN-γ receptor (IFN-γR)(−/−) mice resulted in substantial production of IL-4 and other T...

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Detalles Bibliográficos
Autores principales: Zhang, Yongkang, Apilado, Ron, Coleman, John, Ben-Sasson, Shlomo, Tsang, Sharon, Hu-Li, Jane, Paul, William E., Huang, Hua
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193457/
https://www.ncbi.nlm.nih.gov/pubmed/11457891