Cargando…
Toward a Defined Anti-Leishmania Vaccine Targeting Vector Antigens: Characterization of a Protective Salivary Protein
Leishmania parasites are transmitted to their vertebrate hosts by infected phlebotomine sand fly bites. Sand fly saliva is known to enhance Leishmania infection, while immunity to the saliva protects against infection as determined by coinoculation of parasites with vector salivary gland homogenates...
Autores principales: | Valenzuela, Jesus G., Belkaid, Yasmine, Garfield, Mark K., Mendez, Susana, Kamhawi, Shaden, Rowton, Edgar D., Sacks, David L., Ribeiro, José M.C. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193460/ https://www.ncbi.nlm.nih.gov/pubmed/11489952 |
Ejemplares similares
-
Development of a Natural Model of Cutaneous Leishmaniasis: Powerful Effects of Vector Saliva and Saliva Preexposure on the Long-Term Outcome of Leishmania major Infection in the Mouse Ear Dermis
por: Belkaid, Yasmine, et al.
Publicado: (1998) -
The Role of Interleukin (IL)-10 in the Persistence of Leishmania major in the Skin after Healing and the Therapeutic Potential of Anti–IL-10 Receptor Antibody for Sterile Cure
por: Belkaid, Yasmine, et al.
Publicado: (2001) -
Immunity to Distinct Sand Fly Salivary Proteins Primes the Anti-Leishmania Immune Response towards Protection or Exacerbation of Disease
por: Oliveira, Fabiano, et al.
Publicado: (2008) -
Comparative salivary gland transcriptomics of sandfly vectors of visceral leishmaniasis
por: Anderson, Jennifer M, et al.
Publicado: (2006) -
Immunity to Sand Fly Salivary Protein LJM11 Modulates Host Response to Vector-Transmitted Leishmania Conferring Ulcer-Free Protection
por: Gomes, Regis, et al.
Publicado: (2012)