Phosphoinositide 3-Kinase–Dependent Membrane Recruitment of P62(dok) Is Essential for Its Negative Effect on Mitogen-Activated Protein (Map) Kinase Activation

A major pathway by which growth factors, such as platelet-derived growth factor (PDGF), regulate cell proliferation is via the receptor tyrosine kinase/Ras/mitogen-activated protein kinase (MAPK) signaling cascade. The output of this pathway is subjected to tight regulation of both positive and nega...

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Detalles Bibliográficos
Autores principales: Zhao, Mingming, Schmitz, Arndt A.P., Qin, Yi, Di Cristofano, Antonio, Pandolfi, Pier Paolo, Van Aelst, Linda
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193463/
https://www.ncbi.nlm.nih.gov/pubmed/11489946

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