P62(dok), a Negative Regulator of Ras and Mitogen-Activated Protein Kinase (Mapk) Activity, Opposes Leukemogenesis by P210(bcr-abl)

p62(dok) has been identified as a substrate of many oncogenic tyrosine kinases such as the chronic myelogenous leukemia (CML) chimeric p210(bcr-abl) oncoprotein. It is also phosphorylated upon activation of many receptors and cytoplamic tyrosine kinases. However, the biological functions of p62(dok)...

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Detalles Bibliográficos
Autores principales: Di Cristofano, Antonio, Niki, Masaru, Zhao, Mingming, Karnell, Fredrick G., Clarkson, Bayard, Pear, Warren S., Van Aelst, Linda, Pandolfi, Pier Paolo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193466/
https://www.ncbi.nlm.nih.gov/pubmed/11489947

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